Hyaluronic acid: main characteristics and advantages, methods of application

Hyaluronic acid under the Clearsoft trademark

Hyaluronic acid (HA) is one of the most famous cosmetic ingredients, familiar even to the average consumer. It is a mucopolysaccharide obtained from plant sources and has excellent moisturizing and film-forming properties that depend on its molecular weight.

The higher the molecular weight of HA, the more pronounced the film-forming properties. Thus, high molecular weight HA reduces transepidermal moisture loss by creating a light film on the skin surface and maintaining hydration of the stratum corneum. The lower the molecular weight of HA, the stronger its biological activity. Medium molecular weight HA is more easily dissolved in water, penetrates into the deep layers of the skin, moisturizes the skin, reduces wrinkles, and reduces sebum production. Low molecular weight HA penetrates deeper layers of the skin, moisturizing it, improving texture and barrier functions.

HA will help maintain the elasticity and firmness of the skin, giving it smoothness, softness and a more youthful appearance due to its moisturizing properties. It is an ideal ingredient for moisturizers, creams, serums and body lotions, as well as products for sensitive skin.

Chemical properties of our products

  • Quality: CosmeticGrade
  • INCI: SodiumHyaluronate
  • Chemical formula: (C14H21NO11)n

High quality, low impurity content:

  • GC>95%, protein<0.1%,
  • total aerobic acid<10 CFU/g,
  • mold and yeast <10 CFU/g

Molecular weight range from 3 kDa to 2500 kDa

Trade Name Molecular weight Molecular weight
CLEARSOFT M-HA 2,0 >2000 kDa High molecular weight
CLEARSOFT M-HA 1,5 – 2,0 1500~ 2000 kDa High molecular weight
CLEARSOFT M-HA 0,8 – 1,5 800 ~1500 kDa Average molecular weight
CLEARSOFT M-HA 100 – 800 100 ~ 800 kDa Average molecular weight
CLEARSOFT M-HA 8-50 8 ~ 50 kDa Low molecular weight
CLEARSOFT M-HA Oligo <10 kDa Oligo

Application in cosmetics

  • Daily use – 0.01-0.20%
  • Skin repair and night use products – 0.02-0.20%
  • After-sun products – 0.02-0.50%
  • Pre/after shave products – 0.002-0.05%

Solubility

  • It dissolves quickly in water.
  • It is soluble in mixtures of water with ethyl alcohol, isopropyl alcohol, propylene glycol and butylene glycol at concentrations of up to 70% organic solvent.
  • Insoluble in
    water-immiscible solvents.

Clearsoft HA Oral Care

It is a GK for oral care. It has an excellent film-forming effect, therefore it prevents the formation of plaque, and also reduces transepidermal moisture loss, which prevents the oral cavity from drying out. It is suitable for use in oral care products: toothpastes, mouthwashers, sprays, gels.
Recommended input percentage: 0.05-0.5%.

Derivatives of hyaluronic acid

ClearsoftHA 4D

INCI: Sodium Hyaluronate Crosspolymer, Sodium hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Phenoxyethanol, Ethylhexylglycerin, Water.

An ideal combination of four different types of GC is used to form a three-dimensional mesh on the skin. Due to this, the product acts on all layers of the skin, forming a flexible moisturizing film that reduces transepidermal moisture loss and moisturizes the deep layers of the skin. When applying Clearsoft HA4D to the skin, it can focus on different layers of the skin (stratum corneum, epidermis and dermis). This allows for instant three-dimensional moisturizing efficiency, reduces transepidermal moisture loss, and moisturizes the deep layers of the skin.
Recommended input percentage: 1-10%

ClearsoftHA +

INCI: Hydroxypropyltrimonium Hyaluronate.

This is a unique type of GC that has a positive charge. It is characterized by high adhesion to hair, resistance to rinsing and excellent moisturizing effect of hyaluronate sodium. GK’s “Moisturizing Veil” wraps dry and damaged hair, keeping it hydrated and shiny. ClearsoftHA+ is natural and mild, suitable for hair and scalp care, can significantly increase the hydration and hydration of the scalp, reduce itching and dandruff caused by dry scalp and narrowed pores.
Recommended input percentage: 0.01–1.0%

ClearsoftHA Oil

INCI: Sodium Hyaluronate, MeadowfoamSeed Oil.

The product is obtained by combining HA and soap nut oil using a unique microsphere technology. It is ideal for decorative cosmetics, which are mainly anhydrous formulations: lipstick, foundation, eye shadow, blush.
Clearsoftha Oil moisturizes and nourishes the skin, reduces dryness and roughness.
Recommended input percentage: 0.1–2.0 %

ClearsoftHA DSE

INCI: Dimethylsilanol Hyaluronic Acid Ester.

The product is obtained as a result of the reaction of HA with organosilicon compounds. It has anti-aging properties: it stimulates collagen production, increases skin elasticity. It restores and moisturizes the skin, promotes the renewal of the epidermis, supports cellular metabolism and strengthens the protective barrier of the skin.
Recommended input percentage: 4.0–6.0 %

ClearsoftHA Elastomer

INCI: Sodium Hyaluronate Crosspolymer, Ethylhexylglycerin, Phenoxyethanol, Water.

A high-molecular polymer crosslinked with HA forms a breathable protective film on the skin that enhances barrier functions, moisturizes the skin, and gives it a long-lasting feeling of softness and smoothness.
Recommended input percentage: 1.0–5.0%

Clearsoft Tremella

INCI: Tremella Fuciformis Polysaccharide.

Tremella is a polysaccharide obtained from the edible part of a snow mushroom. Clearsoft Tremella contains glucuronic acid, which is also the main component of HA. Clearsoft Tremella has a stronger moisture retention capacity than GK itself, and is also known as vegetable GK. The skin becomes nourished, radiant and hydrated. The product also adapts to the humidity of the climate: in dry climates, it improves the moisture–retaining ability of the skin, and in wet climates, it reduces the load in the form of excessive moisture. In addition, Clearsoft Tremella exhibits antioxidant and anti-aging properties.
Recommended input percentage: 0.01–0.5%

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